Intracellular motility: How can we all work together?

Intracellular motility: How can we all work together?

Recent results reinforce the view that actin-based and microtubule-based motility systems do not operate independently, but are used in coordinated fashion to determine intracellular localization of cargo such as organelles.

Intracellular Transport: How Do Motors Work Together?

How many motors move cargos on microtubules inside a cell, and how do they work together to achieve regulated transport? A new study uses an optical trap to investigate the motion of protein-bound beads on the surface of flagella to address these questions and comes up with some intriguing answers.

Flagellar Motility: All Pull Together

Eukaryotic flagella produce a swimming force by coordinating thousands of dynein motor proteins. Recent work provides new clues into how this coordination is achieved.

How can we make them work ?

All bleeding stops: how we can help...

Rossaint and colleagues provide the critical care community with a comprehensive review of evidence-based data in an updated European guideline on management of bleeding following major trauma. In addition to reevaluating and grading recommendations carried forward from their previous work, they present new recommendations in areas such as coagulation support and monitoring, tourniquet usage, c...